Supplementary Figure 2: GITR and OX40 are diminished on Treg cell progenitors from Cd28-/- mice on the C57BL/6 background. | Nature Immunology

Supplementary Figure 2: GITR and OX40 are diminished on Treg cell progenitors from Cd28-/- mice on the C57BL/6 background.

From: Costimulation via the tumor-necrosis factor receptor superfamily couples TCR signal strength to the thymic differentiation of regulatory T cells

Supplementary Figure 2

Histograms plotted in the top panels showing GITR and OX40 expression are derived by gating on Treg cell progenitors from Cd28-/- mice (red histograms) and their wild type littermates (B6 background; blue histograms). In the lower panels, cumulative data are shown for the expression of GITR and OX40 on Treg cell progenitors from CD28-deficient mice in comparison to wild type littermates (mean ± SEM, n=3, p-values generated by student's T-test).

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