Supplementary Figure 2: Composition of B lymphocytes, T lymphocytes and Treg cells in lymphoid tissues and cLP of Uhrf1+/+Cd4-Cre and Cd4creUhrf1fl/flCd4-Cre mice. | Nature Immunology

Supplementary Figure 2: Composition of B lymphocytes, T lymphocytes and Treg cells in lymphoid tissues and cLP of Uhrf1+/+Cd4-Cre and Cd4creUhrf1fl/flCd4-Cre mice.

From: The epigenetic regulator Uhrf1 facilitates the proliferation and maturation of colonic regulatory T cells

Supplementary Figure 2

a, Schematic representation of the genomic structure of wild-type murine Uhrf1 gene, the resultant mutant allele generated by homologous recombination and carrying the neomycin resistance gene (Neo), and the locus after removal of the Neo gene. Exons are indicated by boxes. b-d, Lymphocytes in cLP, mesenteric lymph node (MLN), spleen and thymus of Cd4CreUhrf1+/+ (+/+) and Cd4CreUhrf1fl/fl (fl/fl) mice at 5 weeks of age were characterized by flow cytometry. The frequency of Treg cells were analyzed by flow cytometory (d). Data are representative of at least three independent experiments with similar results

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