Supplementary Figure 1: Analysis of claudin expression in human colonic samples | Nature Immunology

Supplementary Figure 1: Analysis of claudin expression in human colonic samples

From: TH9 cells that express the transcription factor PU.1 drive T cell–mediated colitis via IL-9 receptor signaling in intestinal epithelial cells

Supplementary Figure 1

Total mRNA was isolated from 24-35 human samples of human control tissue or IBD tissue. Expression of PIAS1, SOCS3, CLDN1 and CLDN2 mRNA in human colonic tissue of IBD patients was analyzed. SOCS3 and CLDN2 mRNA levels were up regulated in active UC patient samples. Significant differences are indicated.

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