Supplementary Figure 4: AP4 is required for the population expansion of antigen-specific CD8+ T cells after infection with WNV.
From: c-Myc-induced transcription factor AP4 is required for host protection mediated by CD8+ T cells
Statistical analysis showing absolute numbers of total CD8+ T cells (a), H-2Db–NS4B-specific T cells as determined by H-2Db–NS4B tetramer binding (b) or intracellular staining for IFN-γ following NS4B peptide stimulation (c) in the spleen on day 7 after WNV infection. Data is from one experiment using five Tfap4–/–, four Tfap4F/F CD8-Cre+, and four control age- and sex-matched C57BL/6 mice. * P < 0.05, NS: not significant by Mann Whitney U-test. Each symbol represents an individual mouse; small horizontal lines indicate median.
