Supplementary Figure 1: Overexpression of Ym1 reduces eosinophil numbers in the lungs. | Nature Immunology

Supplementary Figure 1: Overexpression of Ym1 reduces eosinophil numbers in the lungs.

From: Chitinase-like proteins promote IL-17-mediated neutrophilia in a tradeoff between nematode killing and host damage

Supplementary Figure 1

(a-d) Absolute numbers per mg of tissue of CD8+ T cells (a), CD4+ T cells (b), CD19+ CD11b- B cells (c) and SigF+ CD11c- CD11b+ eosinophils (d) in the lungs of BALB/c wild-type mice transfected intranasally with 20 μg pCDNA3.1 control or plasmids encoding BRP-39, Ym1 or Ym2. Lungs were collected 48 h after transfection. NS not significant; *P < 0.05 compared to pcDNA3.1 transfected mice (analysis of variance with Tukey-Kramer HSD multiple comparison test). Data are pooled from two independent experiments (a-d; mean ± s.e.m., five to nine mice per group).

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