Supplementary Figure 4: Schematic for the simultaneous adoptive transfer of multiple congenic naive CD5lo or CD5hi CD8+ T cells. | Nature Immunology

Supplementary Figure 4: Schematic for the simultaneous adoptive transfer of multiple congenic naive CD5lo or CD5hi CD8+ T cells.

From: The TCR's sensitivity to self peptide–MHC dictates the ability of naive CD8+ T cells to respond to foreign antigens

Supplementary Figure 4

Peripheral CD8 T cells from 4-8 congenic donors were negatively enriched and then equal numbers from each donor were combined. CD44lo CD5lo and CD5hi cells were flow sorted and then the indicated number of each individual donor population was transferred into congenic recipients. Mice were infected the next day with LM-B8R and the B8R/Kb-specific response was assessed 7 days later using tetramer enrichment

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