Supplementary Figure 1: Brg1 is required for the orchestration of early B cell development. | Nature Immunology

Supplementary Figure 1: Brg1 is required for the orchestration of early B cell development.

From: The chromatin remodeler Brg1 activates enhancer repertoires to establish B cell identity and modulate cell growth

Supplementary Figure 1

Flow cytometric analysis of B-lineage cells derived from Smarca4fl/+Il7rCre/+ and Smarca4fl/flIl7rCre/+ mice. BM cells were gated on the Gr1CD11bTer119CD19+B220+ population and segregated into early pro-B (CD43+CD24intBP1), late pro-B (CD43+CD24intBP1+), large pre-B (CD43+CD24hiFSChi) and small pre-B (CD43IgM) cells as shown on top panel. Cell numbers are indicated for Smarca4fl/+Il7rCre/+ and Smarca4fl/flIl7rCre/+ mice (lower panel). Data representative of two independent experiments. **P < 0.01 (two-tailed unpaired Student’s t test).

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