Supplementary Figure 6: Antimicrobial and cytotoxic activities of rhIL-26 and LL-37.
From: TH17 cells promote microbial killing and innate immune sensing of DNA via interleukin 26
Viable bacteria and human neutrophils, monocytes, macrophages, pDCs and HEK cells following overnight culture in the presence of increasing concentrations of rhIL-26 (a) or LL-37 (b). MIC50 for bacteria and EC50 for human cells were calculated using nonlinear regression fit curves. Data are representative of two independent experiments. Error bars represent the s.d. of duplicate wells.
