Supplementary Figure 1: A bifurcating model with strictly asymmetric cell divisions of the naïve cells fails to account for the data.
From: CD8+ T cell diversification by asymmetric cell division
(a) Model scheme of a bifurcating model that assumes strictly asymmetric cell divisions of the naïve cells into one pre-TM and one TSLE cell (dA), followed by proliferation of pre-TM and TSLE cells with subset-specific rates (λ1 and λ2, respectively). (b) Comparison of experimental data derived from single-cell fate mapping (white bars and open dots; same data as in Fig. 1d) with the best-fit of the model depicted in a (blue bars or curve).
