Supplementary Figure 2: Mir22–/– mice develop reduced TH17 responses upon sensitization with ovalbumin. | Nature Immunology

Supplementary Figure 2: Mir22–/– mice develop reduced TH17 responses upon sensitization with ovalbumin.

From: The microRNA miR-22 inhibits the histone deacetylase HDAC4 to promote TH17 cell–dependent emphysema

Supplementary Figure 2

Both WT and Mir22–/– mice were intraperitoneally injected with 25µg ovalbumin precipitated in alum weekly for three consecutive weeks. Total splenocytes were harvested at the end of the fifth week. (a) IFN-γ, (b) IL-4 and (c) IL-17A positive cells with ovalbumin (OVA; 0.5 mg/ml overnight) and without (Media) were quantified by ELISpot. *: p<0.05, Kruskal Wallis test. n=4.

Back to article page