Supplementary Figure 1: miR-22 is required for airway MMP activities but not for the development of γδ+ T cells in emphysema. | Nature Immunology

Supplementary Figure 1: miR-22 is required for airway MMP activities but not for the development of γδ+ T cells in emphysema.

From: The microRNA miR-22 inhibits the histone deacetylase HDAC4 to promote TH17 cell–dependent emphysema

Supplementary Figure 1

(a) Gelatin zymogram depicting matrix metalloproteinase (MMP) 2 and MMP9 activities in bronchoalveolar lavage fluid (BALF) of wild type (WT; lanes 3-5) and Mir22–/– mice (lanes 6-9) previously challenged with nCB. Lanes 1 and 2 are BALF from naïve wild type mice. (b) Total lung IL-17A+ γδ+ T cells were quantified by flow cytometry.

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