Supplementary Figure 8: Type II interferon restrains IL-33-mediated inflammation. | Nature Immunology

Supplementary Figure 8: Type II interferon restrains IL-33-mediated inflammation.

From: Type I interferon restricts type 2 immunopathology through the regulation of group 2 innate lymphoid cells

Supplementary Figure 8

Wild type (WT) C57BL/6 mice (five age- and sex-matched animals per group) were challenged intranasally with PBS as control, IFN-γ, IL-33, or IL-33 + IFN-γ for three consecutive days. 24 hours after the last treatment pulmonary expression of (a) Il6, (b) Ccl17, (c) Ccl22, (d) Chi3l3, (e) Fn1 and (f) Ccl24 was determined by qRT-PCR. The bars represent the mean ± standard deviation of each cohort. Data are representative of two independent experiments. The asterisks indicate statistically significant differences (*, p ≤ 0.05; **, p ≤ 0.01; ***, p ≤ 0.001).

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