Supplementary Figure 4: Structures of 42F3 TCR–agonistic peptides. | Nature Immunology

Supplementary Figure 4: Structures of 42F3 TCR–agonistic peptides.

From: Structural interplay between germline interactions and adaptive recognition determines the bandwidth of TCR-peptide-MHC cross-reactivity

Supplementary Figure 4

(a) The overall structure of the 42F3 complex recognizing second-generation synthetic peptides presented by mini-H-2Ld. (b) The 2Fo-Fc map of peptides (yellow sticks) in electron density (blue mesh) contoured for 1-1.5σ. (c) The overall structure of the 42F3 complex recognizing first-generation synthetic peptides presented by mini-H-2Ld. (d) The 2Fo-Fc map of peptides (yellow sticks) in electron density (blue mesh) is contoured for 1-1.5σ.

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