Supplementary Figure 1: Transport of long-chain fatty acids into the mitochondrial matrix. | Nature Immunology

Supplementary Figure 1: Transport of long-chain fatty acids into the mitochondrial matrix.

From: Fatty acid oxidation in macrophage polarization

Supplementary Figure 1

Schematic demonstrating the role of CPT1 located on the outer mitochondrial membrane (OMM) and CPT2 on the inner mitochondrial membrane (IMM) in transporting long chain FAs in the form of Acyl-CoA into the mitochondrial matrix. The drug etomoxir is thought to function as a CPT1 inhibitor.

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