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Protein glycosylation energizes T cells

Nutrient transport is regulated by signaling pathways that together indicate metabolic checkpoints in T cell self-renewal, differentiation and proliferation.

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Figure 1: Nutrient access and cellular signaling are linked by UDP-GlcNAc and OGT in the proliferation, transformation and self-renewal of T cells.

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Correspondence to Jamey D Marth.

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Yang, W., Marth, J. Protein glycosylation energizes T cells. Nat Immunol 17, 613–614 (2016). https://doi.org/10.1038/ni.3468

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