Supplementary Figure 3: Overall significantly deregulated probes and pathways.
From: Tumor-induced stromal reprogramming drives lymph node transformation
(a) Heatmap displaying all gene probes with a cutoff of change in expression of 1.5-fold for day and day 11 TDLNs. (b) Heatmap displaying normalized enrichment scores (NES) above 1.5 and with a P<0.05 for deregulated Kyoto Encyclopedia of Genes and Genomes (KEGG) pathways using GSEA. (c) Heatmap of z-scores (indicating activation or inhibition) of canonical pathways Ingenuity Pathway Analysis (IPA) above 0.5 and P<0.05 (left) and top canonical pathways (IPA) ordered according to their P values (right). (d) Heatmap displaying z-scores (indicating activation or inhibition) of disease and biofunctions (IPA) above 2 and P<0.05 (left), and biofunctions (IPA) ordered according to their P values (right). Grey boxes represent pathways/functions with no significant deregulation.
