Supplementary Figure 4: rLC interacts with the negative regulator Pirk.
From: The regulatory isoform rPGRP-LC induces immune resolution via endosomal degradation of receptors
(a) Quantification of Dpt mRNA expression over time in flies overexpressing rLC (c564-Gal4 > UAS-rLCx), Pirk (c564-Gal4 > UAS-Pirk) or both in the fat body after challenge with heat-killed Ecc15. Control, driver c564-Gal4 (see Fig. 4d).
(b) Quantification of Dpt mRNA expression over time in flies with genomic Pirk deficiency and overexpressing rLC in the fat body (driver: w;c564-Gal4) after challenge with heat-killed Ecc15 (see Fig. 4e). *** P < 0.001 (one-way ANOVA, Tukey’s post hoc test (a, b). Data are pooled from three independent experiments and represent mean + s.e.m.
