Supplementary Figure 3: Effect of the silencing of microglial caspase-3 on the expression of Il6, Ccl22, Chil3, Mmp14 and Nos2 in mono- or coculture microglia.
From: Glioma-induced inhibition of caspase-3 in microglia promotes a tumor-supportive phenotype
Analysis of the expression of different genes in microglia cells transfected with the indicated siRNA cultured in medium alone or segregated coculture for 6 hours with GL261 glioma cells. Results are presented relative to those of Ctrl siRNA transfected BV2 cells cultured alone, set as 1. Statistics and error bars: mean ± s.e.m. n=6 of biological replicates. Data were analyzed using two-tailed Student’s t-test. *P< 0.05; **P< 0.01; ***P< 0.001; ****P< 0.0001.
