Supplementary Figure 7: Expanded analysis of ‘IL-21 rescue’ experiments.
From: Suppression by TFR cells leads to durable and selective inhibition of B cell effector function
(a) Cell count (left), IgG1+ staining (middle) and Glut1 expression (right) on B cells from suppression assays in which IL21, IL6 or IL4 were added. (b) Cell count (left), IgG1+ staining (middle) and Glut1 expression (right) on B cells from suppression assays in which WT or Il21r-/- B cells were cultured as well as IL-21. (c) Heat map of genes downregulated in activated versus suppressed B cells, but not rescued with the addition of IL-21.
