Supplementary Figure 5: Il6ra−/− BMDCs are not deficient in the production of pro-inflammatory cytokines in response to stimulation with LPS. | Nature Immunology

Supplementary Figure 5: Il6ra−/− BMDCs are not deficient in the production of pro-inflammatory cytokines in response to stimulation with LPS.

From: Trans-presentation of IL-6 by dendritic cells is required for the priming of pathogenic TH17 cells

Supplementary Figure 5

Control Il6raflox/flox or IL-6Rα deficient BMDCs (Il6raΔDC) were stimulated over night with either IL-6 or LPS followed by analysis of Il1b, Il6, Il12a, Il12b, and Il23 mRNA production by quantitative RT PCR. Mean + SD of technical replicates. One out of two independent experiments. *P<0.05, ANOVA plus Sidak’s multiple comparisons test.

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