Supplementary Figure 4: Themis2 is not limiting in the antibody response to NP-Ficoll and NP19-CGG. | Nature Immunology

Supplementary Figure 4: Themis2 is not limiting in the antibody response to NP-Ficoll and NP19-CGG.

From: Themis2 lowers the threshold for B cell activation during positive selection

Supplementary Figure 4

(a) IgM and IgG3 anti-NP antibody titers in wild-type (WT) and Themis2-/- mice immunized with the T-independent antigen 4-hydroxy-3-nitrophenylacetyl (NP)-Ficoll. Symbols represent individual mice, and bars means and s.e.m.. (b) IgG1 anti-NP4 and anti-NP25 antibody titres in WT and Themis2-/- mice 7 and 14 days after primary immunization with the T-dependent antigen NP19-chicken γ-globulin (NP19-CGG) and at 44 days, 5 days after boosting with NP19-CGG. Symbols represent individual mice, bars means and s.e.m..

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