Supplementary Figure 2: FcμR does not control BM B cell output.
From: The IgM receptor FcμR limits tonic BCR signaling by regulating expression of the IgM BCR
(a) Shown are frequencies (left) and numbers (right) of B cell precursors in Fcmr flx/flxCd19-Cre and control BMs (n=4 mice/group). (b,c) Fcmr flx/flxCd19-Cre and control mice (n = 3-4 mice/group) were sublethally irradiated (350rd) and peripheral B cell pools were analyzed 12 days after irradiation. Shown are the frequencies and numbers ± SD of (b) transitional (CD93+) and (c) total (CD19+) B cells in BM and spleen as assessed by multicolor flow cytometry. Data in (a) are representative of at least two independent experiments (mean ± SD in a-c). Data did not show significant differences by unpaired two-tailed Student’s t-test (p > 0.05).
