Supplementary Figure 5: Development of gd TCR repertoires after alloHSCT. | Nature Immunology

Supplementary Figure 5: Development of gd TCR repertoires after alloHSCT.

From: Human γδ T cells are quickly reconstituted after stem-cell transplantation and show adaptive clonal expansion in response to viral infection

Supplementary Figure 5

(a) NGS analysis of patients without CMV reactivation before and after alloHSCT. Box plots display median and range of Vγ2, Vγ3, Vγ4, Vγ5, Vγ8 and Vγ9 as well as Vγ1, Vδ2, Vδ3 and Vδ5 chains. (b) Shannon diversity calculation of all TRG and TRD repertoires from patients before and up to 180 days after alloHSCT. Samples were randomly sampled to 20,000 productive rearrangements. Vertical lines show medians. (c) TRG repertoires of all cord blood, healthy controls and patients before and up to 180 days after alloHSCT were separated into Vγ9+ clones to calculate frequencies of Vγ9JP+ clones. Horizontal lines represent median values.

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