Supplementary Figure 4: Module relationship, annotation enrichment maps and CD4 TEMRA cytotoxicity.
From: Social network architecture of human immune cells unveiled by quantitative proteomics
(a) PCA of proteins in module 29 and its representative cell types. Projections and loadings are displayed. Cell types are color-coded as in Fig. 1. Cytolytic proteins shared between CD4 TEMRA, NK and CD8 T cells are labelled in red. Expression profile of GZMB is displayed as an example.
(b) Heat map of module correlation coefficients.
(c) Enrichment map of module 17. Nodes are annotation terms, edges represent gene overlap between terms. Node size represent annotation enrichment, fill color indicates adjusted p value.
(d) Enrichment map of module 19. Labels as in panel B.
