Supplementary Figure 2: Metabolic parameters of obese Cre+α4f/f and Cre−α4f/f mice.
From: A self-sustained loop of inflammation-driven inhibition of beige adipogenesis in obesity
a) The weights of SAT, VAT and liver of obese Cre+α4f/f and Cre−α4f/f mice (fed a HFD for 20 weeks) are shown (n=8 Cre+α4f/f mice and n=9 Cre−α4f/f mice). b) Quantification of adipocyte cell diameter of SAT (n=5 mice/group) and VAT (n=4 mice/group) and fitting curve of obese Cre+α4f/f (black line) and Cre−α4f/f mice (grey line). Left: quantification of adipocyte cell size and fitting curve is shown. Right: Mean adipocyte diameter is shown. c) Fasting blood levels of glucose (Glu), triglycerides (TG), and cholesterol (Chol) from obese Cre+α4f/f and Cre−α4f/f mice are shown (n=14 Cre+α4f/f mice and n=15 Cre−α4f/f mice). Data are presented as mean ± SEM. *P < 0.05. Student's t-test in (a) and (c), Mann-Whitney U-test in (b). Data in (a) are pooled from 3 experiments; data in (b) are from one experiment; data in (c) are pooled from 5 experiments.
