Supplementary Figure 8: Nrros−/− PLCs do not resemble activated microglia.
From: Mice deficient in NRROS show abnormal microglial development and neurological disorders
(a - c) Gene expression of indicated cytokines from RNA-seq of Nrros+/+ (WT) microglia, PVM and Nrros-/- (KO) PLCs (n = 3). (d - f) Basal cytokine levels secreted by cultured myeloid cells isolated from WT and KO brains. (g) Heat map showing top 30 differentially expressed genes between WT PVM and KO PLCs. N = 3. Error bar: ± SEM. *P < 0.05; **P < 0.01; ***P < 0.001. Unpaired Student’s t-test. 12-week old animals were used.
