Supplementary Figure 1: Nrros-/- mice show distended bladder and normal relative mass of major organs.
From: Mice deficient in NRROS show abnormal microglial development and neurological disorders
Representative H&E stained images of (a - b) bladder (bar = 500 μm), (c - d) ureter, (e - f) renal papillary epithelium (bar = 100 μm) and (g-h) renal glomerulus (bar = 50 μm) from Nrros+/+ and Nrros-/- animals. Graphs depicting the mass of gastrocnemius (i), tibialis (j), brain (k) and kidney (l) as percent body weight in Nrros+/+ and Nrros-/- animals. Arrow, outer smooth muscle wall; *, transitional epithelium. N ≥ 8. Error bar: ± SEM. Animals were 13 - 15 weeks old.
