Supplementary Figure 2: Infection with MuHV-4 impairs HDM-induced airway allergy in young mice. | Nature Immunology

Supplementary Figure 2: Infection with MuHV-4 impairs HDM-induced airway allergy in young mice.

From: A gammaherpesvirus provides protection against allergic asthma by inducing the replacement of resident alveolar macrophages with regulatory monocytes

Supplementary Figure 2

(a-d) Quantification of MuHV-4 genomic copies in splenic cells by qPCR (a) and of MuHV-4 specific immunoglobulins in sera by ELISA (b), histological analysis of lung sections (scale bars, 100 μm) (c), total and differential cell counts of BALF cells (d), at euthanasia of mock or MuHV-4-infected 3 weeks old BALB/c mice, submitted 30 days p.i. to the HDM-induced high dose model of asthma. Data are mean ± s.e.m. of samples from 5 mice per group. *** p< 0.001, ** p< 0.01 and * p < 0.05 (Two-way (a, b) or One-way (d) ANOVA and Tukey's multiple comparison test).

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