Serum IgE concentrations are kept low to avoid potential allergic complications. New data show how Id2 suppresses class switching to the ε isotype and reduces IgE expression.
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Maizels, N. Yin outwits Yang at the IgE locus. Nat Immunol 4, 7–8 (2003). https://doi.org/10.1038/ni0103-7
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DOI: https://doi.org/10.1038/ni0103-7
