Dendritic cells have the unique capacity of processing soluble exogenous proteins for presentation to killer T lymphocytes. Now Cresswell and associates show that this is possible because pinocytosed material gains access to the perinuclear endoplasmic reticulum of dendritic cells.
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Saveanu, L., van Endert, P. Dendritic cells: open for presentation business. Nat Immunol 6, 7–8 (2005). https://doi.org/10.1038/ni0105-7
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DOI: https://doi.org/10.1038/ni0105-7
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