Experiments based on the requirement for immunoglobulin gene transcription provide new insights into the elusive role played by AID in immunoglobulin class switching and hypermutation.
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References
Manis, J.P., Tian, M. & Alt, F.W. Trends Immunol. 23, 31–39 (2002).
Honjo, T., Kinoshita, K. & Muramatsu, M. Annu. Rev. Immunol. 20, 165–196 (2002).
Yu, K.F., Chedin, F., Hsieh, C.-L., Wilson, T.E. & Lieber, M.R. Nat. Immunol. 4, 442–451 (2003).
Ramiro, A.R., Stavropoulos, P., Jankovic, M. & Nussenzweig, M.C. Nat. Immunol. 4, 452–456 (2003).
Shinkura, R. et al. Nat. Immunol. 4, 435–441 (2003).
Muramatsu, M. et al. J. Biol. Chem. 274, 18470–18476 (1999).
Di Noia, J. & Neuberger, M.S. Nature 419, 43–48 (2002).
Rada, C. et al. Curr. Biol. 12, 1748–1755 (2002).
Chaudhuri, J. et al. Nature 422, 726–730 (2003).
Dickerson, S.K., Market, E., Besmer, E. & Papavasiliou, F.N. J. Exp. Med. in press (2003).
Bransteitter, R., Pham, P., Scharff, M.D. & Goodman, M.F. Proc. Natl. Acad. Sci. USA 100, 4102–4107 (2003).
Doi, T., Kinoshita, K., Ikegawa, M., Muramatsu, M. & Honjo, T. Proc. Natl. Acad. Sci. USA 100, 2634–2638 (2003).
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Fugmann, S., Schatz, D. RNA AIDs DNA. Nat Immunol 4, 429–430 (2003). https://doi.org/10.1038/ni0503-429
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DOI: https://doi.org/10.1038/ni0503-429
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