Skip to main content

Thank you for visiting nature.com. You are using a browser version with limited support for CSS. To obtain the best experience, we recommend you use a more up to date browser (or turn off compatibility mode in Internet Explorer). In the meantime, to ensure continued support, we are displaying the site without styles and JavaScript.

  • Letters to the Editor
  • Published:

Therapeutic replication-competent herpes virus

Nature Medicine volume 4, page 133 (1998)Cite this article

Access through your institution
Buy or subscribe

This is a preview of subscription content, access via your institution

Access options

Access through your institution

Buy this article

  • Purchase on SpringerLink
  • Instant access to full article PDF
Buy now

Prices may be subject to local taxes which are calculated during checkout

References

  1. Martuza, R.L. Act locally, think globally. Nature Med. 12, 1323 (1997).

    Article  Google Scholar 

  2. Maclean, A.R. et al. Herpes simplex virus type 1 deletion variants 1714 and 1716 pinpoint neurovirulence related sequences in Glasgow strain 17+ between immediate eariy gene 1 and the ‘a’ sequence. J. Gen. Virol. 72,631–639 (1991).

    Article  CAS  Google Scholar 

  3. Kesari, S. et al. A mutant herpes simplex virus replicates in brain tumours but not in neurons derived from a human embryonal carcinoma cell line. Lab. Invest. 73, 636-648 (1995).

    CAS  PubMed  Google Scholar 

Download references

Author information

Author notes

  1. G. Cruickshank

    Present address: University Dept. Neurosurgery, Queen Elizabeth Hospital, Birmingham, UK

Authors and Affiliations

  1. Glasgow University Dept. of Clinical Oncology, Beatson Oncology Centre, Glasgow, G116NT, UK

    R. Rampling

  2. Glasgow University Dept. of Neurosurgery, Southern General Hospital, Glasgow, G514TF, UK

    G. Cruickshank

  3. Glasgow University Division of virology, Institute of Virology, Glasgow, G11 5JR, UK

    A. Maclean

  4. Neurovirology Research Laboratories, Institute of Neurological Science, Glasgow, G51 4TF, UK

    M. Brown

Authors
  1. R. Rampling
    View author publications

    Search author on:PubMed Google Scholar

  2. G. Cruickshank
    View author publications

    Search author on:PubMed Google Scholar

  3. A. Maclean
    View author publications

    Search author on:PubMed Google Scholar

  4. M. Brown
    View author publications

    Search author on:PubMed Google Scholar

Rights and permissions

Reprints and permissions

About this article

Cite this article

Rampling, R., Cruickshank, G., Maclean, A. et al. Therapeutic replication-competent herpes virus. Nat Med 4, 133 (1998). https://doi.org/10.1038/nm0298-133c

Download citation

  • Issue date:

  • DOI: https://doi.org/10.1038/nm0298-133c

This article is cited by

Search

Advanced search

Quick links

Nature Briefing

Sign up for the Nature Briefing newsletter — what matters in science, free to your inbox daily.

Get the most important science stories of the day, free in your inbox. Sign up for Nature Briefing