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HIV swiftly guts the immune system

Two studies show that SIV directly kills massive numbers of immune cells in the gut within days of infection. The results come on the heels of similarly dramatic findings for HIV, and could radically shift the focus of HIV research and therapy.

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Figure 1: HIV's lair.

Katherine Ris

Figure 2: Depleting the gut.

Li et al., reprinted from Nature

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Veazey, R., Lackner, A. HIV swiftly guts the immune system. Nat Med 11, 469–470 (2005). https://doi.org/10.1038/nm0505-469

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