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Multidrug resistance: Locked in the vault?

Nature Medicine volume 1, page 527 (1995)Cite this article

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References

  1. Scheffer, G.L. et al. The drug resistance-related protein LRP is the human major vault protein. Nature Med. 1, 578–582 (1995).

    Article  CAS  Google Scholar 

  2. Kedersha, N.L. & Rome, L.H. Isolation and characterization of a novel ribonucleoprotein particle: Large structures contain a single species of small RNA. J. Cell Biol. 103, 699–709 (1986).

    Article  CAS  Google Scholar 

  3. Rome, L., Kedersha, N. & Chugani, D. Unlocking vaults: Organelles in search of a function. Trends Cell Biol. 1, 47–50 (1991).

    Article  CAS  Google Scholar 

  4. Chugani, D.C., Rome, L.H. & Kedersha, N.L. Localization of vault particles to the nuclear pore complex. J. Cell Sci. 106, 23–29 (1993).

    CAS  PubMed  Google Scholar 

  5. Kickhoefer, V.A. et al. Vault RNP particles from rat and bullfrog contain a related small RNA that is transcribed by RNA polymerase III. J. biol. Chem. 268, 7868–78173 (1993).

    CAS  PubMed  Google Scholar 

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Authors and Affiliations

  1. Department of Biological Chemistry, UCLA School of Medicine, Los Angeles, California, 90024, USA

    Leonard H. Rome

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  1. Leonard H. Rome
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Rome, L. Multidrug resistance: Locked in the vault?. Nat Med 1, 527 (1995). https://doi.org/10.1038/nm0695-527

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