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Dangerous signals from E. coli toxin

Nature Medicine volume 6, pages 741–742 (2000)Cite this article

α-hemolysin is a pore-forming cytolysin involved in the virulence of uropathogenic Escherichia coli strains. Recent studies have shown that at sublytic concentrations, this toxin can also induce calcium oscillations that affect gene expression, the inflammatory response and other cellular activities.

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Figure 1: Linear model of E. coli α-hemolysin (HlyA).

Bob Crimi

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Authors and Affiliations

  1. Institute of Medical Microbiology, University of Frankfurt am Main,, Paul-Ehrlich-Straße 40, Frankfurt am Main, 60596, Germany

    Albrecht Ludwig

  2. Department of Microbiology, Biocenter, University of Würzburg, Am Hubland, Würzburg, 97074, Germany

    Werner Goebel

Authors
  1. Albrecht Ludwig
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  2. Werner Goebel
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Ludwig, A., Goebel, W. Dangerous signals from E. coli toxin. Nat Med 6, 741–742 (2000). https://doi.org/10.1038/77456

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