Abnormal vessel growth in the eyes is a major cause of blindness. In mice, injection of stem cells from the bone marrow can alter vessel growth (pages 1004–1010).
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References
Anonymous. Early photocoagulation for diabetic retinopathy. ETDRS report number 9. Early Treatment Diabetic Retinopathy Study Research Group. Ophthalmology 98, 766–785 (1991).
Aiello, L.P. Clinical implications of vascular growth factors in proliferative retinopathies. Curr. Opin. Ophthalmol. 8, 19–31 (1997).
Otani, A. et al. Bone marrow–derived stem cells cells target retinal astrocytes and have pro- or anti-angiogenic activity. Nature Med. 8, 1004–1010 (2002).
Grant, M.B. et al. Adult hematopoietic stem cells provide functional hemangioblast activity during retinal neovascularization. Nature Med. 8, 607–612 (2002).
Otani, A. et al. A fragment of human TrpRS as a potent antagonist of ocular angiogenesis. Proc. Natl. Acad. Sci. USA 99, 178–183 (2002).
Robinson, G.S. et al. Nonvascular role for VEGF: VEGFR-1, 2 activity is critical for neural retinal development. FASEB J. 15, 1215–1217 (2001).
Mukouyama, Y.S., Shin, D., Britsch, S., Taniguchi, M. & Anderson, D.J. Sensory nerves determine the pattern of arterial differentiation and blood vessel branching in the skin. Cell 109, 693–705 (2002).
Hattori, K. et al. Placental growth factor reconstitutes hematopoiesis by recruiting VEGFR1+ stem cells from bone-marrow microenvironment. Nature Med. 8, 841–849 (2002).
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Smith, L. Stem cells go for the eyes. Nat Med 8, 932–934 (2002). https://doi.org/10.1038/nm0902-932
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DOI: https://doi.org/10.1038/nm0902-932