Molecules that recognize pathogens and activate the immune response are being discovered at a rapid rate. RIG-I, a new protein in this category, recognizes viral RNA. Recent studies show that RIG-I operates independently of Toll-like receptors and that it is targeted for inactivation by the hepatitis C virus.
This is a preview of subscription content, access via your institution
Access options
Subscribe to this journal
Receive 12 print issues and online access
$259.00 per year
only $21.58 per issue
Buy this article
- Purchase on SpringerLink
- Instant access to full article PDF
Prices may be subject to local taxes which are calculated during checkout
Katie Ris
References
Kato, H. et al. Immunity 23, 19–28 (2005).
Foy, E. et al. Proc. Natl. Acad. Sci. USA 102, 2986–29891 (2005).
Breiman, A. et al. J. Virol. 79, 3969–3978 (2005).
Yoneyama, M. et al. Nat. Immunol. 5, 730–737 (2004).
Liu, Y.J. Annu. Rev. Immunol. 23, 275–306 (2005).
Honda, K. et al. Nature 434, 1035–1040 (2005).
Theofilopoulos, A.N., Baccala, R., Beutler, B. & Kono, D.H. Annu. Rev. Immunol. 23, 307–336 (2005).
Kovacsovics, M. et al. Curr. Biol. 12, 838–843 (2002).
Balachandran, S., Thomas, E. & Barber, G.N. Nature 432, 401–405 (2004).
Zhong, J. et al. Proc. Natl. Acad. Sci. USA 102, 9294–9299 (2005).
Sumpter, R. Jr. et al. J. Virol. 79, 2689–2699 (2005).
Author information
Authors and Affiliations
Rights and permissions
About this article
Cite this article
Benedict, C., Ware, C. RIGing a virus trap. Nat Med 11, 929–930 (2005). https://doi.org/10.1038/nm0905-929
Issue date:
DOI: https://doi.org/10.1038/nm0905-929
