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Reply to “Retrovirus–mediated p53 gene therapy”
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  • Letters to the Editor
  • Published: 01 November 1996

Reply to “Retrovirus–mediated p53 gene therapy”

  • Jack A. Roth1 

Nature Medicine volume 2, page 1163 (1996)Cite this article

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References

  1. Roth, J.A. et al. Retrovirus-mediated wild-type p53 gene transfer to tumors of patients with lung cancer. Nature Med. 2, 985–991 (1996).

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  2. Flaman, J.M. et al. A simple p53 functional assay for screening cell lines, blood, and tumors. Proc. Natl. Acad. Sci. USA 92, 3963–3967 (1995).

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  3. Tada, M. et al. Clonality and stability of the p53 gene in human astrocytic tumor cells — quantitative analysis of p53 gene mutations by yeast functional assay. Int. J. Cancer 67, 447–450 (1996).

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  4. Temin, H.M. Evolution of cancer genes as a mutation-driven process. Cancer Res. 48, 1697–1701 (1988).

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  5. Flaman, J.M. et al. A rapid PCR fidelity assay. Nucleic Acids Res. 22, 3259–3260 (1994).

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  6. Finlay, C.A., Hinds, P.W. & Levine, A.J. The p53 proto-oncogene can act as a suppressor of transformation. Cell 57, 1083–1093 (1989).

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  7. Dittmer, D. et al. Gain of function mutations in p53 . Nature Genet. 4, 42–45 (1993).

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Author information

Authors and Affiliations

  1. Thoracic and Cardiovascular Department, M.D. Anderson Cancer Center, 1515 Hokombe Boulevard, Box 109, Houston, Texas, 77030, USA

    Jack A. Roth

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  1. Jack A. Roth
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Roth, J. Reply to “Retrovirus–mediated p53 gene therapy”. Nat Med 2, 1163 (1996). https://doi.org/10.1038/nm1196-1163b

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  • Issue date: 01 November 1996

  • DOI: https://doi.org/10.1038/nm1196-1163b

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