An electrochemical gene-delivery method enables rapid modification of gene expression in postmitotic neurons in vivo, changing their identity and connectivity pattern.
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References
De la Rossa, A. et al. In vivo reprogramming of circuit connectivity in postmitotic neocortical neurons. Nat. Neurosci. 16, 193–200 (2013).
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Pastrana, E. A back door to the neuron. Nat Methods 10, 190 (2013). https://doi.org/10.1038/nmeth.2390
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DOI: https://doi.org/10.1038/nmeth.2390