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Stem cells

Changing one cell type into another

Two independent groups identify factors that drive direct conversion to oligodendrocyte precursor cells in the rodent.

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References

  1. Heinäniemi, M. et al. Gene-pair expression signatures reveal lineage control. Nat. Methods 10, 577–583 (2013).

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  2. Najm, F.J. et al. Transcription factor–mediated reprogramming of fibroblasts to expandable, myelinogenic oligodendrocyte progenitor cells. Nat. Biotechnol. 31, 426–433 (2013).

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de Souza, N. Changing one cell type into another. Nat Methods 10, 459 (2013). https://doi.org/10.1038/nmeth.2500

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