Two independent groups identify factors that drive direct conversion to oligodendrocyte precursor cells in the rodent.
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References
Heinäniemi, M. et al. Gene-pair expression signatures reveal lineage control. Nat. Methods 10, 577–583 (2013).
Najm, F.J. et al. Transcription factor–mediated reprogramming of fibroblasts to expandable, myelinogenic oligodendrocyte progenitor cells. Nat. Biotechnol. 31, 426–433 (2013).
Yang, N. et al. Generation of oligodendroglial cells by direct lineage conversion. Nat. Biotechnol. 31, 434–439 (2013).
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de Souza, N. Changing one cell type into another. Nat Methods 10, 459 (2013). https://doi.org/10.1038/nmeth.2500
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DOI: https://doi.org/10.1038/nmeth.2500