Optogenetic tools enable light-mediated control over transcription and epigenetic states in specific endogenous loci of the mammalian genome.
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References
Konermann, S. et al. Optical control of mammalian endogenous transcription and epigenetic states. Nature doi:10.1038/nature12466 (23 July 2013).
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Pastrana, E. Light on genome function. Nat Methods 10, 817 (2013). https://doi.org/10.1038/nmeth.2622
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DOI: https://doi.org/10.1038/nmeth.2622