Figure 4: Predictive power and overlap of subtypes derived from different TCGA datasets. | Nature Methods

Figure 4: Predictive power and overlap of subtypes derived from different TCGA datasets.

From: Network-based stratification of tumor mutations

Figure 4

(a) Predictive power in ovarian cancer. For each data type (line color), the power for predicting patient survival time beyond clinical indicators is shown as a function of number of subtypes. (b) Significance of overlap of ovarian cancer subtypes identified by each data type (line color) with subtypes identified by NBS. The table shows the number of patients shared between each NBS subtype and those defined by the TCGA using gene expression. (c) Predictive power in lung cancer, as for a. (d) Significance of overlap of lung cancer subtypes with NBS, as for b. (e) Association between uterine cancer subtype and tumor histology (y axis) as a function of the number of subtypes. P value of significance is indicated by concentric circles as in Figure 3. Colors are as in other panels, symbols have been omitted for clarity. (f) Significance of overlap of uterine cancer subtypes with NBS, as for b. Dashed horizontal lines indicate the P = 0.05 threshold of significance.

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