A set of 16 TetR proteins specific for their synthetic promoters will allow the construction of complex genetic circuits.
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References
Stanton, B.C. et al. Genomic mining of prokaryotic repressors for orthogonal logic gates. Nat. Chem. Biol. 10, 99–105 (2014).
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Rusk, N. Orthogonal logic gates. Nat Methods 11, 132 (2014). https://doi.org/10.1038/nmeth.2830
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DOI: https://doi.org/10.1038/nmeth.2830