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Gene expression

Single cells make the tissue

By pushing throughput, single-cell transcript profiling can replace marker-based sorting and bulk RNA sequencing to redefine tissues from the bottom up.

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References

  1. Jaitin, D.A. et al. Massively parallel single-cell RNA-seq for marker-free decomposition of tissues into cell types. Science 343, 776–779 (2014).

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Nawy, T. Single cells make the tissue. Nat Methods 11, 371 (2014). https://doi.org/10.1038/nmeth.2916

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