Supplementary Figure 10: Application of TPs on substrates with complex topography.
From: A DNA-based molecular probe for optically reporting cellular traction forces
DIC (a) and thresholded fluorescence (b) images of a polarized fibroblast on substrates composed of raised 2 um wide PDMS ridges stamped with TP6. Cell is outlined in yellow and ridges are false-colored magenta. Scale bar is 10 µm. (c) Angular histogram of the distribution of force-bearing adhesions as reported by HPs with respect to the axis of polarization. The mean angle of n=52 adhesions analyzed was 25º (red dashed line).
