Supplementary Figure 1: A two-factor nested design scenario with different number of replicates and different variance at each layer.
From: Sources of variation
For a given layer (e.g. mouse), also shown is the variance of the mean of observations for all deeper layers (e.g. cell + technical). Xijk corresponds to the k measurement of cell j from mouse i. Dots in the subscript correspond to average over those subscripts (e.g. Xi.. is the average of cell and technical replicates for mouse i).
