Supplementary Figure 4: RGEN-induced digenome sequencing to capture off-target sites.
From: Digenome-seq: genome-wide profiling of CRISPR-Cas9 off-target effects in human cells
(a-d) Representative IGV images obtained using the HBB-specific RGEN at the potential off-target sites OT1 (a), OT3 (b), OT7 (c), and OT12 (d). An indel is indicated by an arrow (a) or shown in a box (b).
