Supplementary Figure 1: Liability distributions in balanced case-control data sets.
From: Accurate liability estimation improves power in ascertained case-control studies
Individuals with liability greater than the prevalence-specific cutoff are cases, and the remainder are controls. The liabilities of controls and of cases follow a zero-mean normal distribution, conditioned on being smaller or greater than the liability cutoff, respectively. The distribution of case liabilities becomes increasingly sharply peaked as prevalence decreases.
