Supplementary Figure 3: Sensitivity to read depth and library quality.
From: Identification of active transcriptional regulatory elements from GRO-seq data
(a,b) dREG sensitivity at a 10% false discovery rate at the indicated read depth or asymptotic library complexity. Dotted lines indicate a model that has been trained specifically on the indicated library. Solid lines indicate the model trained on the native K562 PRO-seq libraries. Pink and cyan denote GRO-cap sites and pairs, respectively. (c,d) SVR threshold required to achieve a 10% FDR for SVR models that have (dotted) or have not (solid) been trained specifically to the indicated parameters.
