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Genomics

Splitting Cas9

Nature Methods volume 12, pages 384–385 (2015)Cite this article

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Two research groups show that the CRISPR system can be regulated by heterodimerizing a split Cas9.

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References

  1. Wright, A.V. et al. Rational design of a split-Cas9 enzyme complex. Proc. Natl. Acad. Sci. USA 112, 2984–2989 (2015).

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  2. Zetsche, B. et al. A split-Cas9 architecture for inducible genome editing and transcription modulation. Nat. Biotechnol. 33, 139–142 (2015).

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Authors
  1. Nicole Rusk
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Rusk, N. Splitting Cas9. Nat Methods 12, 384–385 (2015). https://doi.org/10.1038/nmeth.3387

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